Mus musculus Protein: Rai14
Summary
InnateDB Protein IDBP-622572.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rai14
Protein Name retinoic acid induced 14
Synonyms 1700008J19Rik; 1700020L11Rik; Ankycorbin; mKIAA1334; Norpeg;
Species Mus musculus
Ensembl Protein ENSMUSP00000126325
InnateDB Gene IDBG-129474 (Rai14)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm, cell cortex {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly nuclear in nonconfluent cells (By similarity). Associated with the cortical actin cytoskeleton structures in terminal web and cell-cell adhesion sites and stress fibers. {ECO:0000250, ECO:0000269PubMed:11168586}.
Disease Associations
Tissue Specificity Highly expressed in seminiferous tubules of testis. Expressed in ganglion cell layer and in Muller cell fibers of the retina (at protein level). In small intestine highly expressed at the apical and lateral borders of absorptive epithelia. In liver highly expressed along the bile canaliculi. {ECO:0000269PubMed:11042181, ECO:0000269PubMed:11168586}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 14 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005856 cytoskeleton
GO:0005938 cell cortex
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1922896
InterPro IPR002110 Ankyrin repeat
IPR010989 t-SNARE
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9EP71
PhosphoSite PhosphoSite-Q9EP71
TrEMBL
UniProt Splice Variant
Entrez Gene 75646
UniGene Mm.212395
RefSeq NP_001159880
MGI ID
MGI Symbol Rai14
OMIM
CCDS CCDS37043
HPRD
IMGT
EMBL AF202315 AF274866 AK129333 AK141233 BC052458
GenPept AAG24483 AAG25937 AAH52458 BAC98143 BAE24605