Version 5.4
Mus musculus Protein: Eif1a
Summary
InnateDB Protein IDBP-622584.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif1a
Protein Name eukaryotic translation initiation factor 1A
Synonyms C76390; Ef1a; Eftu; eIF-1A; eIF-4C; Eif4c;
Species Mus musculus
Ensembl Protein ENSMUSP00000132018
InnateDB Gene IDBG-145347 (Eif1a)
Protein Structure
UniProt Annotation
Function Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
Protein Structure and Domains
PDB ID MGI:95298
InterPro IPR001253 Translation initiation factor 1A (eIF-1A)
IPR006196 RNA-binding domain, S1, IF1 type
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF01176
PRINTS
PIRSF
SMART SM00652
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q60872
PhosphoSite PhosphoSite-Q60872
TrEMBL Q4FJR7
UniProt Splice Variant
Entrez Gene 13664
UniGene Mm.401710
RefSeq
MGI ID
MGI Symbol Eif1a
OMIM
CCDS CCDS29233
HPRD
IMGT
EMBL AF026481 AK009026 AK013268 AK019451 AK150673 AK150677 AK166368 AK167333 BC027437 CH466528 CT010335 U28419
GenPept AAB05664 AAC63934 AAH27437 BAB26034 BAB28759 BAB31727 BAE29755 BAE29757 BAE38735 BAE39435 CAJ18543 EDL09976 EDL09977 EDL09978

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca