Version 5.4
Mus musculus Protein: Zdhhc23
Summary
InnateDB Protein IDBP-622920.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zdhhc23
Protein Name zinc finger, DHHC domain containing 23
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000128650
InnateDB Gene IDBG-161300 (Zdhhc23)
Protein Structure
UniProt Annotation
Function Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in the brain. {ECO:0000269PubMed:15603741}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008270 zinc ion binding
GO:0019706 protein-cysteine S-palmitoyltransferase activity
Biological Process
GO:0018345 protein palmitoylation
GO:0072659 protein localization to plasma membrane
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2685625
InterPro IPR001594 Zinc finger, DHHC-type, palmitoyltransferase
PFAM PF01529
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5Y5T3
PhosphoSite PhosphoSite-Q5Y5T3
TrEMBL
UniProt Splice Variant
Entrez Gene 332175
UniGene Mm.327852
RefSeq NP_001007461
MGI ID
MGI Symbol Zdhhc23
OMIM
CCDS CCDS28180
HPRD
IMGT
EMBL AK137472 AK147553 AY668949 BC139052 BC145684
GenPept AAI39053 AAI45685 AAU89703 BAE23368 BAE27992

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca