InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sdr42e1

Summary

InnateDB Protein

IDBP-623011.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sdr42e1

Protein Name

short chain dehydrogenase/reductase family 42E, member 1

Synonyms

4632417N05Rik; AI117603;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133782

InnateDB Gene

IDBG-195184 (Sdr42e1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003824	catalytic activity
GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0008831	dTDP-4-dehydrorhamnose reductase activity
GO:0016491	oxidoreductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662	coenzyme binding

Biological Process

GO:0006694	steroid biosynthetic process
GO:0008150	biological_process
GO:0008152	metabolic process
GO:0009058	biosynthetic process
GO:0044237	cellular metabolic process
GO:0045226	extracellular polysaccharide biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005575	cellular_component
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1921282

InterPro

IPR001509 NAD-dependent epimerase/dehydratase
IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
IPR003869 Polysaccharide biosynthesis protein, CapD-like domain
IPR005913 dTDP-4-dehydrorhamnose reductase
IPR013120 Male sterility, NAD-binding

PFAM

PF01370
PF00106
PF01073
PF02719
PF04321
PF07993

PRINTS

PR00080

PIRSF

PIRSF000126

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt