Version 5.4
Mus musculus Protein: Engase
Summary
InnateDB Protein IDBP-623636.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Engase
Protein Name endo-beta-N-acetylglucosaminidase
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000126050
InnateDB Gene IDBG-214652 (Engase)
Protein Structure
UniProt Annotation
Function Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:2443788
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BX80
PhosphoSite PhosphoSite-Q8BX80
TrEMBL
UniProt Splice Variant
Entrez Gene 217364
UniGene Mm.473963
RefSeq
MGI ID
MGI Symbol Engase
OMIM
CCDS
HPRD
IMGT
EMBL AK048667 AK084254 AK167142 AL591075 BC120924
GenPept AAI20925 BAC33415 BAC39149 BAE39287 CAM15758

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca