Version 5.4
| Mus musculus Protein: Arhgap8 | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-623922.2 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | Arhgap8 | ||||
| Protein Name | Rho GTPase activating protein 8 | ||||
| Synonyms | 3110043J09Rik; | ||||
| Species | Mus musculus | ||||
| Ensembl Protein | ENSMUSP00000132008 | ||||
| InnateDB Gene | IDBG-262368 (Arhgap8) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. {ECO:0000250}. | ||||
| Subcellular Localization | |||||
| Disease Associations | |||||
| Tissue Specificity | Highly expressed in skeletal muscle, lung and testis, and at lower levels in kidney, stomach and colon. Not detected in heart, liver, spleen, breast, brain, neonatal head or pancreas. {ECO:0000269PubMed:15225876}. | ||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | MGI:1920417 | ||||
| InterPro |
IPR000198
Rho GTPase-activating protein domain IPR001251 CRAL-TRIO domain IPR008936 Rho GTPase activation protein |
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| PFAM |
PF00620
PF00650 PF13716 |
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| PRINTS | |||||
| PIRSF | |||||
| SMART |
SM00324
SM00516 |
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| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | Q9CXP4 | ||||
| PhosphoSite | PhosphoSite- | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 73167 | ||||
| UniGene | |||||
| RefSeq | NP_082731 | ||||
| MGI ID | |||||
| MGI Symbol | Arhgap8 | ||||
| OMIM | |||||
| CCDS | CCDS27712 | ||||
| HPRD | |||||
| IMGT | |||||
| EMBL | AK014171 AK086816 BC005563 BC010306 | ||||
| GenPept | AAH05563 AAH10306 BAB29190 BAC39750 | ||||