InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gcnt4

Summary

InnateDB Protein

IDBP-624084.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gcnt4

Protein Name

glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000130496

InnateDB Gene

IDBG-606083 (Gcnt4)

Protein Structure

UniProt Annotation

Function

Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity (By similarity). {ECO:0000250}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity
GO:0008375	acetylglucosaminyltransferase activity

Biological Process

GO:0002121	inter-male aggressive behavior
GO:0006486	protein glycosylation
GO:0042403	thyroid hormone metabolic process
GO:0048729	tissue morphogenesis
GO:0048872	homeostasis of number of cells
GO:0060993	kidney morphogenesis