Version 5.4
Homo sapiens Protein: COX5B
Summary
InnateDB Protein IDBP-62467.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COX5B
Protein Name cytochrome c oxidase subunit Vb
Synonyms COXVB;
Species Homo sapiens
Ensembl Protein ENSP00000258424
InnateDB Gene IDBG-62465 (COX5B)
Protein Structure
UniProt Annotation
Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular Localization Mitochondrion inner membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004129 cytochrome-c oxidase activity
GO:0046872 metal ion binding
Biological Process
GO:0007585 respiratory gaseous exchange
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:0045087 innate immune response (InnateDB)
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005743 mitochondrial inner membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002124 Cytochrome c oxidase, subunit Vb
PFAM PF01215
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P10606
PhosphoSite PhosphoSite-P10606
TrEMBL
UniProt Splice Variant
Entrez Gene 1329
UniGene
RefSeq NP_001853
HUGO HGNC:2269
OMIM 123866
CCDS CCDS2032
HPRD 00467
IMGT
EMBL AC017099 BC006229 BT006742 M19961 M59250 U41284
GenPept AAA52060 AAA52061 AAB19185 AAH06229 AAP35388 AAY24279

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca