InnateDB Protein
|
IDBP-625046.2
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Ggta1
|
Protein Name
|
glycoprotein galactosyltransferase alpha 1, 3
|
Synonyms
|
alpha3GalT; AW108479; Gal; GALT; Ggta; Ggta-1;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000132408
|
InnateDB Gene
|
IDBG-164632 (Ggta1)
|
Protein Structure
|
|
Function |
Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose- alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isoglobotrihexosylceramide or isogloboside 3 (iGb3). {ECO:0000269PubMed:12626403}.
|
Subcellular Localization |
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
Accession |
GO Term |
GO:0016758
|
transferase activity, transferring hexosyl groups
|
GO:0046872
|
metal ion binding
|
GO:0047276
|
N-acetyllactosaminide 3-alpha-galactosyltransferase activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:95704
|
InterPro |
IPR005076
Glycosyl transferase, family 6
IPR029044
Nucleotide-diphospho-sugar transferases
|
PFAM |
PF03414
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P23336
|
PhosphoSite |
PhosphoSite-P23336
|
TrEMBL |
Q3TXW0
|
UniProt Splice Variant |
|
Entrez Gene |
14594
|
UniGene |
Mm.480642
|
RefSeq |
|
MGI ID |
|
MGI Symbol |
Ggta1
|
OMIM |
|
CCDS |
CCDS50576
|
HPRD |
|
IMGT |
|
EMBL |
AF297609
AF297610
AF297611
AF297612
AF297613
AF297614
AF297615
AK159087
M26925
M85153
|
GenPept |
AAA37657
AAA37711
AAK97205
AAK97206
BAE34805
|
|
|