InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Plec

Summary

InnateDB Protein

IDBP-625094.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Plec

Protein Name

plectin

Synonyms

AA591047; AU042537; EBS1; PCN; Plec1; PLTN;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000129543

InnateDB Gene

IDBG-153069 (Plec)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.

Experimentally validated
Total	19 [view]
Protein-Protein	18 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	44 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0008307	structural constituent of muscle
GO:0030506	ankyrin binding

Biological Process

GO:0031581	hemidesmosome assembly
GO:0045087	innate immune response (InnateDB)
GO:0046417	chorismate metabolic process

Cellular Component

GO:0005856	cytoskeleton
GO:0005925	focal adhesion
GO:0030056	hemidesmosome
GO:0042383	sarcolemma
GO:0043292	contractile fiber
GO:0045111	intermediate filament cytoskeleton

Protein Structure and Domains

PDB ID

MGI:1277961

InterPro

IPR001101 Plectin repeat
IPR001715 Calponin homology domain
IPR018159 Spectrin/alpha-actinin
IPR020822 Chorismate mutase, type II
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain

PFAM

PF00681
PF00307
PF01817
PF11971

PRINTS

PIRSF

SMART

SM00250
SM00033
SM00150

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite