InnateDB Protein
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IDBP-625358.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Eapp
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Protein Name
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E2F-associated phosphoprotein
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Synonyms
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1810011O16Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000130251
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InnateDB Gene
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IDBG-139557 (Eapp)
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Protein Structure
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Function |
May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
GO:0008284
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positive regulation of cell proliferation
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GO:0032968
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positive regulation of transcription elongation from RNA polymerase II promoter
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GO:0034244
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negative regulation of transcription elongation from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
MGI:1913516
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InterPro |
IPR019370
E2F-associated phosphoprotein
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PFAM |
PF10238
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q5BU09
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PhosphoSite |
PhosphoSite-Q5BU09
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
66266
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UniGene |
Mm.416371
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RefSeq |
XP_006516205
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MGI ID |
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MGI Symbol |
Eapp
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OMIM |
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CCDS |
CCDS25910
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HPRD |
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IMGT |
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EMBL |
AK007442
AK012800
AY882557
BC037622
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GenPept |
AAH37622
AAX20161
BAB25042
BAB28479
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