InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mgat5

Summary

InnateDB Protein

IDBP-625430.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mgat5

Protein Name

mannoside acetylglucosaminyltransferase 5

Synonyms

4930471A21Rik; 5330407H02Rik; AI480971; GlcNAc-TV;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000129166

InnateDB Gene

IDBG-189006 (Mgat5)

Protein Structure

UniProt Annotation

Function

Catalyzes the addition of N-acetylglucosamine in beta 1- 6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides (By similarity). {ECO:0000250}.

Subcellular Localization

Golgi apparatus membrane; Single-pass type II membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008375	acetylglucosaminyltransferase activity
GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

Biological Process

GO:0006487

protein N-linked glycosylation

Cellular Component

GO:0000139	Golgi membrane
GO:0005794	Golgi apparatus
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:894701

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8R4G6

PhosphoSite

PhosphoSite-Q8R4G6

TrEMBL

Q059T5

UniProt Splice Variant

Entrez Gene

107895

UniGene

RefSeq

MGI ID

MGI Symbol

Mgat5

OMIM

CCDS

CCDS15245

HPRD

IMGT

EMBL

AF474154 AK030402 BC125533 BC125535 CH466520

GenPept

AAI25534 AAI25536 AAL83249 BAC26946 EDL39768