Mus musculus Protein: Mest
Summary
InnateDB Protein IDBP-625552.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mest
Protein Name mesoderm specific transcript
Synonyms AA408879; AI256745; Peg1;
Species Mus musculus
Ensembl Protein ENSMUSP00000129639
InnateDB Gene IDBG-133397 (Mest)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:18644838}; Multi-pass membrane protein {ECO:0000269PubMed:18644838}.
Disease Associations
Tissue Specificity Expressed in mesodermal tissues. Isoform 1 is exclusively expressed from the paternal allele in all fetal tissues and cell lines examined, whereas isoform 2 is preferentially expressed from the paternal allele in a tissue- type-specific manner. {ECO:0000269PubMed:7550314}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0010883 regulation of lipid storage
GO:0032526 response to retinoic acid
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:96968
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR000639 Epoxide hydrolase-like
IPR010463 Protein of unknown function DUF1057
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PF06342
PRINTS PR00111
PR00412
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q07646
PhosphoSite PhosphoSite-
TrEMBL D3Z328
UniProt Splice Variant
Entrez Gene 17294
UniGene
RefSeq NP_032616
MGI ID
MGI Symbol Mest
OMIM
CCDS CCDS19979
HPRD
IMGT
EMBL AC146699 AF017994 AF482999 AK032881 AK034949 AK168714 AK168732 AK168743 AK168995 AK169095 AK169266 BC004019 BC006639 CAAA01093966 CAAA01224227 D16262
GenPept AAC53396 AAH04019 AAH06639 AAM78507 BAA03795 BAC28068 BAC28891 BAE40556 BAE40573 BAE40584 BAE40794 BAE40878 BAE41027