InnateDB Protein
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IDBP-625581.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Mmgt2
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Protein Name
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membrane magnesium transporter 2
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000128697
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InnateDB Gene
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IDBG-185229 (Mmgt2)
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Protein Structure
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Function |
Mediates Mg(2+) transport. {ECO:0000269PubMed:18057121}.
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Subcellular Localization |
Golgi apparatus membrane {ECO:0000269PubMed:18057121}; Single-pass type I membrane protein {ECO:0000269PubMed:18057121}. Early endosome membrane {ECO:0000269PubMed:18057121}; Single-pass type I membrane protein {ECO:0000269PubMed:18057121}. Note=Detected in the Golgi apparatus and in post-Golgi vesicles including early endosomes. {ECO:0000269PubMed:18057121}.
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Disease Associations |
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Tissue Specificity |
High expression levels in brain and kidney with lower levels in heart, colon and liver. Very low levels in intestine. In kidney, highest levels in distal convoluted tubule. {ECO:0000269PubMed:18057121}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0005375
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copper ion transmembrane transporter activity
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GO:0005384
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manganese ion transmembrane transporter activity
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GO:0015087
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cobalt ion transmembrane transporter activity
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GO:0015095
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magnesium ion transmembrane transporter activity
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GO:0015099
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nickel cation transmembrane transporter activity
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GO:0022890
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inorganic cation transmembrane transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2448491
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InterPro |
IPR018937
Magnesium transporter
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PFAM |
PF10270
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8R3L0
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PhosphoSite |
PhosphoSite-
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TrEMBL |
G3UWB0
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UniProt Splice Variant |
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Entrez Gene |
216829
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UniGene |
Mm.483841
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RefSeq |
NP_778167
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MGI ID |
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MGI Symbol |
Mmgt2
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OMIM |
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CCDS |
CCDS36179
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HPRD |
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IMGT |
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EMBL |
AK004099
AK131977
AL596181
BC025076
BC096583
CH466601
EU069462
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GenPept |
AAH25076
AAH96583
ABS87352
BAE20417
BAE20917
EDL10362
EDL10363
EDL10364
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