Version 5.4
Mus musculus Protein: Mmgt2
Summary
InnateDB Protein IDBP-625585.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mmgt2
Protein Name membrane magnesium transporter 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000128669
InnateDB Gene IDBG-185229 (Mmgt2)
Protein Structure
UniProt Annotation
Function Mediates Mg(2+) transport. {ECO:0000269PubMed:18057121}.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:18057121}; Single-pass type I membrane protein {ECO:0000269PubMed:18057121}. Early endosome membrane {ECO:0000269PubMed:18057121}; Single-pass type I membrane protein {ECO:0000269PubMed:18057121}. Note=Detected in the Golgi apparatus and in post-Golgi vesicles including early endosomes. {ECO:0000269PubMed:18057121}.
Disease Associations
Tissue Specificity High expression levels in brain and kidney with lower levels in heart, colon and liver. Very low levels in intestine. In kidney, highest levels in distal convoluted tubule. {ECO:0000269PubMed:18057121}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005375 copper ion transmembrane transporter activity
GO:0005384 manganese ion transmembrane transporter activity
GO:0015087 cobalt ion transmembrane transporter activity
GO:0015095 magnesium ion transmembrane transporter activity
GO:0015099 nickel cation transmembrane transporter activity
GO:0022890 inorganic cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0006824 cobalt ion transport
GO:0006825 copper ion transport
GO:0006828 manganese ion transport
GO:0015675 nickel cation transport
GO:0015693 magnesium ion transport
GO:0035434 copper ion transmembrane transport
GO:0035444 nickel cation transmembrane transport
GO:0071421 manganese ion transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0031901 early endosome membrane
Protein Structure and Domains
PDB ID MGI:2448491
InterPro IPR018937 Magnesium transporter
PFAM PF10270
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R3L0
PhosphoSite PhosphoSite-
TrEMBL G3UWB0
UniProt Splice Variant
Entrez Gene 216829
UniGene Mm.483841
RefSeq
MGI ID
MGI Symbol Mmgt2
OMIM
CCDS CCDS36179
HPRD
IMGT
EMBL AK004099 AK131977 AL596181 BC025076 BC096583 CH466601 EU069462
GenPept AAH25076 AAH96583 ABS87352 BAE20417 BAE20917 EDL10362 EDL10363 EDL10364

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca