InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Utf1

Summary

InnateDB Protein

IDBP-625613.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Utf1

Protein Name

undifferentiated embryonic cell transcription factor 1

Synonyms

AI505934;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128848

InnateDB Gene

IDBG-211597 (Utf1)

Protein Structure

UniProt Annotation

Function

Acts as a transcriptional coactivator of ATF2. {ECO:0000269PubMed:9524124}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed mainly in pluripotent cells with expression rapidly down-regulated upon cell differentiation. {ECO:0000269PubMed:9524124}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0071837	HMG box domain binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0008584	male gonad development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1276125

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6J1H4

PhosphoSite

PhosphoSite-Q6J1H4

TrEMBL

B2RSF1

UniProt Splice Variant

Entrez Gene

22286

UniGene

Mm.10205

RefSeq

NP_033508

MGI ID

MGI Symbol

Utf1

OMIM

CCDS

CCDS21958

HPRD

IMGT

EMBL

AB017360 AY606111 BC138841 BC138842 CH466531 D31647

GenPept

AAI38842 AAI38843 AAT38948 BAA25403 BAA82667 EDL17873