InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Msx3

Summary

InnateDB Protein

IDBP-625779.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Msx3

Protein Name

homeobox, msh-like 3

Synonyms

AI323377;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133484

InnateDB Gene

IDBG-211634 (Msx3)

Protein Structure

UniProt Annotation

Function

Acts as a potent transcriptional repressor of MSX1. {ECO:0000269PubMed:11115394}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00108, ECO:0000269PubMed:11115394}.

Disease Associations

Tissue Specificity

Restricted to the dorsal embryonic central nervous system.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007275	multicellular organismal development
GO:0035067	negative regulation of histone acetylation