Version 5.4
Mus musculus Protein: Il18r1
Summary
InnateDB Protein IDBP-625906.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il18r1
Protein Name interleukin 18 receptor 1
Synonyms Il18ralpha; Il1rrp;
Species Mus musculus
Ensembl Protein ENSMUSP00000128277
InnateDB Gene IDBG-148535 (Il18r1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042008 interleukin-18 receptor activity
Biological Process
GO:0030101 natural killer cell activation
GO:0032729 positive regulation of interferon-gamma production
GO:0035655 interleukin-18-mediated signaling pathway
GO:0042346 positive regulation of NF-kappaB import into nucleus
GO:0045063 T-helper 1 cell differentiation
Cellular Component
Protein Structure and Domains
PDB ID MGI:105383
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013151 Immunoglobulin
PFAM PF00047
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8C257
UniProt Splice Variant
Entrez Gene 16182
UniGene Mm.253664
RefSeq NP_001155315
MGI ID
MGI Symbol Il18r1
OMIM
CCDS CCDS48247
HPRD
IMGT
EMBL AC167126 AK089237 BC023240 CH466536
GenPept AAH23240 BAC40807 EDL14577

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca