InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dcn

Summary

InnateDB Protein

IDBP-625962.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dcn

Protein Name

decorin

Synonyms

DC; DSPG2; mDcn; PG40; PGII; PGS2; SLRR1B;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000131431

InnateDB Gene

IDBG-187478 (Dcn)

Protein Structure

UniProt Annotation

Function

May affect the rate of fibrils formation.

Subcellular Localization

Secreted, extracellular space, extracellular matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005518	collagen binding
GO:0005539	glycosaminoglycan binding
GO:0047485	protein N-terminus binding
GO:0050840	extracellular matrix binding

Biological Process

GO:0001822	kidney development
GO:0001890	placenta development
GO:0007519	skeletal muscle tissue development
GO:0007568	aging
GO:0009612	response to mechanical stimulus
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
GO:0032496	response to lipopolysaccharide
GO:0042060	wound healing
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005589	collagen type VI trimer
GO:0005615	extracellular space

Protein Structure and Domains

PDB ID

MGI:94872

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR016352 Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan

PFAM

PF01462
PF00560
PF13504
PF13855

PRINTS

PIRSF

PIRSF002490

SMART

SM00013
SM00369

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt