InnateDB Protein
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IDBP-625975.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Wdr4
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Protein Name
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WD repeat domain 4
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Synonyms
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AI415180; AI448349; D530049K22Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000126061
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InnateDB Gene
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IDBG-164363 (Wdr4)
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Protein Structure
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Function |
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. {ECO:0000255HAMAP-Rule:MF_03056}.
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Subcellular Localization |
Nucleus {ECO:0000255HAMAP-Rule:MF_03056}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
7 [view]
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0008176
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tRNA (guanine-N7-)-methyltransferase activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1889002
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InterPro |
IPR001680
WD40 repeat
IPR017986
WD40-repeat-containing domain
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PFAM |
PF00400
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PRINTS |
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PIRSF |
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SMART |
SM00320
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TIGRFAMs |
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Modification |
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SwissProt |
Q9EP82
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PhosphoSite |
PhosphoSite-Q9EP82
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TrEMBL |
E9Q1L4
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UniProt Splice Variant |
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Entrez Gene |
57773
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UniGene |
Mm.489455
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RefSeq |
NP_067297
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MGI ID |
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MGI Symbol |
Wdr4
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OMIM |
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CCDS |
CCDS28606
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HPRD |
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IMGT |
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EMBL |
AC166172
AJ271892
AJ271893
AK144821
AK152271
AK153161
BC039272
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GenPept |
AAH39272
BAE26082
BAE31087
BAE31771
CAC05584
CAC05585
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