InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pcid2

Summary

InnateDB Protein

IDBP-626043.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pcid2

Protein Name

PCI domain containing 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133204

InnateDB Gene

IDBG-134445 (Pcid2)

Protein Structure

UniProt Annotation

Function

Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. {ECO:0000269PubMed:20870947}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0043066	negative regulation of apoptotic process
GO:0043488	regulation of mRNA stability
GO:0045579	positive regulation of B cell differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0048536	spleen development
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:2000117	negative regulation of cysteine-type endopeptidase activity