Version 5.4
Mus musculus Protein: Grtp1
Summary
InnateDB Protein IDBP-626090.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Grtp1
Protein Name GH regulated TBC protein 1
Synonyms 5430401C05Rik; C81211; Tbc1d6;
Species Mus musculus
Ensembl Protein ENSMUSP00000130324
InnateDB Gene IDBG-134755 (Grtp1)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein for Rab family protein(s).
Subcellular Localization
Disease Associations
Tissue Specificity Highly expressed in testes, expression greatly increased at postnatal day 20 and remained high up to day 90. Moderately expressed in kidney and liver, weakly expressed in intestine, lung, ovaries and stomach. Expression of Growth hormone increased the expression in testis but decreased expression in liver and kidney. {ECO:0000269PubMed:11564724}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID MGI:1914040
InterPro IPR000195 Rab-GTPase-TBC domain
PFAM PF00566
PRINTS
PIRSF
SMART SM00164
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D3N8
PhosphoSite PhosphoSite-Q9D3N8
TrEMBL
UniProt Splice Variant
Entrez Gene 66790
UniGene Mm.407617
RefSeq NP_080044
MGI ID
MGI Symbol Grtp1
OMIM
CCDS CCDS22107
HPRD
IMGT
EMBL AF329833 AK007905 AK017197 AK017251 AK082863 AK149322 BC029096
GenPept AAH29096 AAL67673 BAB25339 BAB30630 BAB30653 BAC38658 BAE28813

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca