InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Timm9

Summary

InnateDB Protein

IDBP-626223.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Timm9

Protein Name

translocase of inner mitochondrial membrane 9 homolog (yeast)

Synonyms

2810011L15Rik; Tim10a; Timm10;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000126298

InnateDB Gene

IDBG-146701 (Timm9)

Protein Structure

UniProt Annotation

Function

Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding
GO:0051087	chaperone binding