Version 5.4
Mus musculus Protein: Rnh1
Summary
InnateDB Protein IDBP-626454.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnh1
Protein Name ribonuclease/angiogenin inhibitor 1
Synonyms AW546468; C80305; RNH;
Species Mus musculus
Ensembl Protein ENSMUSP00000133061
InnateDB Gene IDBG-212016 (Rnh1)
Protein Structure
UniProt Annotation
Function Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008428 ribonuclease inhibitor activity
Biological Process
GO:0043086 negative regulation of catalytic activity
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0032311 angiogenin-PRI complex
Protein Structure and Domains
PDB ID MGI:1195456
InterPro IPR001611 Leucine-rich repeat
IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00368
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91VI7
PhosphoSite PhosphoSite-Q91VI7
TrEMBL
UniProt Splice Variant
Entrez Gene 107702
UniGene Mm.279485
RefSeq NP_001165571
MGI ID 3TSR
MGI Symbol Rnh1
OMIM
CCDS CCDS22002
HPRD
IMGT
EMBL AF071546 AK133822 AK141351 AK147059 BC010331
GenPept AAH10331 AAK68859 BAE21862 BAE24659 BAE27643

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca