Mus musculus Protein: Dennd2c
Summary
InnateDB Protein IDBP-626494.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dennd2c
Protein Name DENN/MADD domain containing 2C
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000127187
InnateDB Gene IDBG-181163 (Dennd2c)
Protein Structure
UniProt Annotation
Function Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0017112 Rab guanyl-nucleotide exchange factor activity
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:3036254
InterPro IPR001194 DENN domain
IPR005112 dDENN domain
IPR005113 uDENN domain
PFAM PF02141
PF03455
PF03456
PRINTS
PIRSF
SMART SM00799
SM00801
SM00800
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P9P8
PhosphoSite PhosphoSite-Q6P9P8
TrEMBL E9Q4E4
UniProt Splice Variant
Entrez Gene 329727
UniGene Mm.293641
RefSeq NP_808525
MGI ID
MGI Symbol Dennd2c
OMIM
CCDS CCDS38572
HPRD
IMGT
EMBL AC150894 AK137637 AK172232 BC046440 BC060666
GenPept AAH46440 AAH60666 BAE23443 BAE42898