Version 5.4
| Mus musculus Protein: Slc19a3 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-626816.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Slc19a3 | ||||||||
| Protein Name | solute carrier family 19 (sodium/hydrogen exchanger), member 3 | ||||||||
| Synonyms | A230084E24Rik; AI788884; ThTr2; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000126646 | ||||||||
| InnateDB Gene | IDBG-174270 (Slc19a3) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | High expression in kidney, brain, lung and small intestine. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1931307 | ||||||||
| InterPro |
IPR002666
Reduced folate carrier IPR011701 Major facilitator superfamily IPR016196 Major facilitator superfamily domain, general substrate transporter |
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| PFAM |
PF01770
PF07690 |
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| PRINTS | |||||||||
| PIRSF |
PIRSF028739
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| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q99PL8 | ||||||||
| PhosphoSite | PhosphoSite-Q99PL8 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 80721 | ||||||||
| UniGene | Mm.261542 | ||||||||
| RefSeq | XP_006496644 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Slc19a3 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS15101 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF271634 BC109154 BC109155 | ||||||||
| GenPept | AAG53880 AAI09155 AAI09156 | ||||||||