Version 5.4
Mus musculus Protein: Slc39a7
Summary
InnateDB Protein IDBP-626909.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc39a7
Protein Name solute carrier family 39 (zinc transporter), member 7
Synonyms AA408174; AI117660; AL024048; H-2Ke4; H2-Ke4; Ke-4; Ke4; Ring5; Zip7;
Species Mus musculus
Ensembl Protein ENSMUSP00000130102
InnateDB Gene IDBG-169480 (Slc39a7)
Protein Structure
UniProt Annotation
Function Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. {ECO:0000269PubMed:15705588}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:15705588, ECO:0000269PubMed:2294398}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006829 zinc ion transport
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:95909
InterPro IPR003689 Zinc/iron permease
PFAM PF02535
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q31125
PhosphoSite PhosphoSite-Q31125
TrEMBL E9PV10
UniProt Splice Variant
Entrez Gene 14977
UniGene Mm.18556
RefSeq NP_001071177
MGI ID
MGI Symbol Slc39a7
OMIM
CCDS CCDS37576
HPRD
IMGT
EMBL AF100956 AK159968 CR974462 M32010
GenPept AAA37767 AAC69903 BAE35522

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca