InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adam3

Summary

InnateDB Protein

IDBP-627039.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adam3

Protein Name

a disintegrin and metallopeptidase domain 3 (cyritestin)

Synonyms

Cyrn1; Taz83; tMDC;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000132651

InnateDB Gene

IDBG-142688 (Adam3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0007338	single fertilization
GO:0007339	binding of sperm to zona pellucida

Cellular Component

GO:0009986	cell surface
GO:0045121	membrane raft

Protein Structure and Domains

PDB ID

MGI:102518

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001762 Blood coagulation inhibitor, Disintegrin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
IPR013111 EGF-like domain, extracellular

PFAM

PF00008
PF01421
PF00200
PF01562
PF08516
PF07974

PRINTS

PR00289

PIRSF

SMART

SM00181
SM00050
SM00608

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F8VQ03

UniProt Splice Variant

Entrez Gene

11497

UniGene

Mm.5168

RefSeq

XP_006509047

MGI ID

MGI Symbol

Adam3

OMIM

CCDS

CCDS22196

HPRD

IMGT

EMBL

AC138355

GenPept