InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pbx2

Summary

InnateDB Protein

IDBP-627363.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pbx2

Protein Name

pre B-cell leukemia transcription factor 2

Synonyms

AU043397; G17;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133766

InnateDB Gene

IDBG-172072 (Pbx2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0009954	proximal/distal pattern formation
GO:0030326	embryonic limb morphogenesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex

Protein Structure and Domains

PDB ID

MGI:1341793

InterPro

IPR001356 Homeobox domain
IPR005542 PBX
IPR009057 Homeodomain-like

PFAM

PF00046
PF03792

PRINTS

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3UR63

UniProt Splice Variant

Entrez Gene

18515

UniGene

Mm.474217

RefSeq

MGI ID

MGI Symbol

Pbx2

OMIM

CCDS

HPRD

IMGT

EMBL

AK141763 AK165859 CT009767

GenPept

BAE24825 BAE38419