Version 5.4
Mus musculus Protein: Ager
Summary
InnateDB Protein IDBP-627373.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ager
Protein Name advanced glycosylation end product-specific receptor
Synonyms RAGE;
Species Mus musculus
Ensembl Protein ENSMUSP00000134401
InnateDB Gene IDBG-172144 (Ager)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006954 inflammatory response
GO:0045087 innate immune response (InnateDB)
GO:0050930 induction of positive chemotaxis
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:893592
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin
IPR013162 CD80-like, immunoglobulin C2-set
PFAM PF07679
PF00047
PF08205
PRINTS
PIRSF
SMART SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C5H3H7
UniProt Splice Variant
Entrez Gene 11596
UniGene Mm.3383
RefSeq NP_001258353
MGI ID
MGI Symbol Ager
OMIM
CCDS CCDS70795
HPRD
IMGT
EMBL CH466666 CT009767 EU570243
GenPept ACE63495 EDL26799

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca