InnateDB Protein
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IDBP-627476.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gtf2e2
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Protein Name
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general transcription factor II E, polypeptide 2 (beta subunit)
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Synonyms
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34kDa; AI462509; C330006J08Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000129834
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InnateDB Gene
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IDBG-147962 (Gtf2e2)
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Protein Structure
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Function |
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000255PROSITE- ProRule:PRU00682}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
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Protein-Protein |
13
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
25 [view]
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Molecular Function |
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Biological Process |
GO:0006355
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regulation of transcription, DNA-templated
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GO:0006367
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transcription initiation from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
MGI:1915403
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InterPro |
IPR003166
Transcription factor TFIIE beta subunit, DNA-binding domain
IPR016656
Transcription initiation factor TFIIE, beta subunit
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PFAM |
PF02186
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PRINTS |
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PIRSF |
PIRSF016398
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D902
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PhosphoSite |
PhosphoSite-Q9D902
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
68153
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UniGene |
Mm.490339
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RefSeq |
NP_080860
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MGI ID |
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MGI Symbol |
Gtf2e2
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OMIM |
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CCDS |
CCDS22236
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HPRD |
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IMGT |
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EMBL |
AK007492
AK088342
AK150415
AK153370
AK158783
BC020016
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GenPept |
AAH20016
BAB25066
BAC40294
BAE29539
BAE31938
BAE34662
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