InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atpif1

Summary

InnateDB Protein

IDBP-627511.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atpif1

Protein Name

ATPase inhibitory factor 1

Synonyms

Atpi; If1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133099

InnateDB Gene

IDBG-194053 (Atpif1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004857	enzyme inhibitor activity
GO:0005515	protein binding
GO:0043532	angiostatin binding

Biological Process

GO:0001937	negative regulation of endothelial cell proliferation
GO:0006783	heme biosynthetic process
GO:0030218	erythrocyte differentiation
GO:0043086	negative regulation of catalytic activity
GO:0045980	negative regulation of nucleotide metabolic process
GO:0072593	reactive oxygen species metabolic process
GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Cellular Component

GO:0005739	mitochondrion
GO:0005753	mitochondrial proton-transporting ATP synthase complex
GO:0009986	cell surface

Protein Structure and Domains

PDB ID

MGI:1196457

InterPro

IPR007648 ATPase inhibitor, IATP, mitochondria

PFAM

PF04568

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9PV44

UniProt Splice Variant

Entrez Gene

11983

UniGene

Mm.2171

RefSeq

MGI ID

MGI Symbol

Atpif1

OMIM

CCDS

HPRD

IMGT

EMBL

AL805897

GenPept