InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ube2g2

Summary

InnateDB Protein

IDBP-627623.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ube2g2

Protein Name

ubiquitin-conjugating enzyme E2G 2

Synonyms

1110003O05Rik; D10Xrf369; UBC7; Ubc7p;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133515

InnateDB Gene

IDBG-167481 (Ube2g2)

Protein Structure

UniProt Annotation

Function

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Involved in endoplasmic reticulum- associated degradation (ERAD) (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016881	acid-amino acid ligase activity

Biological Process

GO:0018279	protein N-linked glycosylation via asparagine
GO:0030433	ER-associated ubiquitin-dependent protein catabolic process
GO:0070936	protein K48-linked ubiquitination