Mus musculus Protein: Klk11
Summary
InnateDB Protein IDBP-627659.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klk11
Protein Name kallikrein related-peptidase 11
Synonyms 2310015I08Rik; Prss20; TLSP;
Species Mus musculus
Ensembl Protein ENSMUSP00000132721
InnateDB Gene IDBG-177414 (Klk11)
Protein Structure
UniProt Annotation
Function Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin (By similarity). {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Expressed in brain and prostate (isoform 1) and prostate (isoform 2). {ECO:0000269PubMed:11072088}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1929977
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QYN3
PhosphoSite PhosphoSite-Q9QYN3
TrEMBL Q9CQ78
UniProt Splice Variant
Entrez Gene 56538
UniGene Mm.154276
RefSeq NP_064358
MGI ID
MGI Symbol Klk11
OMIM
CCDS CCDS39935
HPRD
IMGT
EMBL AB016226 AB016227 AK009360 AK009451 AK009720 AK019102
GenPept BAA36955 BAA88825 BAB26241 BAB26297 BAB26461 BAB31548