InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Katna1

Summary

InnateDB Protein

IDBP-627779.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Katna1

Protein Name

katanin p60 (ATPase-containing) subunit A1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000132514

InnateDB Gene

IDBG-132542 (Katna1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0008568	microtubule-severing ATPase activity
GO:0009378	four-way junction helicase activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0045502	dynein binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001578	microtubule bundle formation
GO:0001764	neuron migration
GO:0006200	ATP catabolic process
GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0007126	meiotic nuclear division
GO:0008104	protein localization
GO:0010977	negative regulation of neuron projection development
GO:0031122	cytoplasmic microtubule organization
GO:0051013	microtubule severing
GO:0051329	interphase of mitotic cell cycle

Cellular Component

GO:0000922	spindle pole
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005811	lipid particle
GO:0005813	centrosome
GO:0005819	spindle
GO:0005874	microtubule
GO:0005886	plasma membrane
GO:0030424	axon
GO:0030426	growth cone
GO:0030496	midbody
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

MGI:1344353

InterPro

IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR007330 MIT
IPR008824 DNA helicase, Holliday junction RuvB type, N-terminal
IPR015415 Vps4 oligomerisation, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00004
PF07724
PF13304
PF04212
PF05496
PF09336

PRINTS

PIRSF

SMART

SM00382
SM00745

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite