InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mybpc2

Summary

InnateDB Protein

IDBP-627844.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mybpc2

Protein Name

myosin binding protein C, fast-type

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000130127

InnateDB Gene

IDBG-178931 (Mybpc2)

Protein Structure

UniProt Annotation

Function

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding

Biological Process

GO:0006936	muscle contraction
GO:0007155	cell adhesion

Cellular Component

GO:0005856	cytoskeleton
GO:0032982	myosin filament

Protein Structure and Domains

PDB ID

MGI:1336170

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5XKE0