Version 5.4
Mus musculus Protein: Neu2
Summary
InnateDB Protein IDBP-627879.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Neu2
Protein Name neuraminidase 2
Synonyms MBS; MSS; MTS;
Species Mus musculus
Ensembl Protein ENSMUSP00000126509
InnateDB Gene IDBG-254372 (Neu2)
Protein Structure
UniProt Annotation
Function Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins, oligosaccharides and gangliosides.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity Highly expressed in heart. {ECO:0000269PubMed:10713120}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0052794 exo-alpha-(2->3)-sialidase activity
GO:0052795 exo-alpha-(2->6)-sialidase activity
GO:0052796 exo-alpha-(2->8)-sialidase activity
Biological Process
GO:0006689 ganglioside catabolic process
GO:0009313 oligosaccharide catabolic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1344417
InterPro IPR002860 BNR repeat
IPR011040 Sialidases
PFAM PF02012
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JMH3
PhosphoSite PhosphoSite-Q9JMH3
TrEMBL Q8R0U7
UniProt Splice Variant
Entrez Gene 23956
UniGene Mm.143717
RefSeq
MGI ID
MGI Symbol Neu2
OMIM
CCDS CCDS15135
HPRD
IMGT
EMBL AB028023 AB048604 AC102564 AC157811 AF139059 BC026408 BC105657 BC105658 BC105659 BC105661 CH466520 FJ613504
GenPept AAH26408 AAI05658 AAI05659 AAI05660 AAI05662 ACM77811 BAA92867 BAB39152 EDL40156 EDL40158

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca