InnateDB Protein
|
IDBP-628037.3
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Csnk2b
|
Protein Name
|
casein kinase 2, beta polypeptide
|
Synonyms
|
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000134218
|
InnateDB Gene
|
IDBG-176640 (Csnk2b)
|
Protein Structure
|
|
Function |
Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). Participates in Wnt signaling. {ECO:0000250, ECO:0000269PubMed:10806215, ECO:0000269PubMed:16818610}.
|
Subcellular Localization |
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 212 interaction(s) predicted by orthology.
Experimentally validated |
Total |
19
[view]
|
Protein-Protein |
19
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
212 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0010862
|
positive regulation of pathway-restricted SMAD protein phosphorylation
|
GO:0016055
|
Wnt signaling pathway
|
GO:0032927
|
positive regulation of activin receptor signaling pathway
|
GO:0033211
|
adiponectin-activated signaling pathway
|
GO:0043537
|
negative regulation of blood vessel endothelial cell migration
|
GO:0045859
|
regulation of protein kinase activity
|
GO:0061154
|
endothelial tube morphogenesis
|
|
Cellular Component |
|
PDB ID |
MGI:88548
|
InterPro |
IPR000704
Casein kinase II, regulatory subunit
|
PFAM |
PF01214
|
PRINTS |
PR00472
|
PIRSF |
|
SMART |
SM01085
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P67871
|
PhosphoSite |
PhosphoSite-P67871
|
TrEMBL |
G3UZA4
|
UniProt Splice Variant |
|
Entrez Gene |
13001
|
UniGene |
|
RefSeq |
XP_006523639
|
MGI ID |
|
MGI Symbol |
Csnk2b
|
OMIM |
|
CCDS |
CCDS28684
|
HPRD |
|
IMGT |
|
EMBL |
AF109719
AK002903
AK010730
AK012369
AK146186
AK161330
BC003775
CR974444
X52959
X56502
X80685
|
GenPept |
AAF03911
AAH03775
BAB22445
BAB27147
BAB28193
BAE26962
BAE36328
CAA37132
CAA39857
CAA56700
|
|
|