InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ddx39b

Summary

InnateDB Protein

IDBP-628156.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ddx39b

Protein Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

Synonyms

0610030D10Rik; AI428441; Bat-1; Bat1; Bat1a; D17H6S81E; D17H6S81E-1; D6S81Eh;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133705

InnateDB Gene

IDBG-177489 (Ddx39b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 54 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	54 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004004	ATP-dependent RNA helicase activity
GO:0005524	ATP binding
GO:0016787	hydrolase activity
GO:0017070	U6 snRNA binding
GO:0030621	U4 snRNA binding
GO:0043008	ATP-dependent protein binding

Biological Process

GO:0000245	spliceosomal complex assembly
GO:0006200	ATP catabolic process
GO:0010501	RNA secondary structure unwinding
GO:0032786	positive regulation of DNA-templated transcription, elongation
GO:0046784	intronless viral mRNA export from host nucleus
GO:2000002	negative regulation of DNA damage checkpoint

Cellular Component

GO:0000346	transcription export complex
GO:0005681	spliceosomal complex
GO:0005687	U4 snRNP
GO:0005688	U6 snRNP
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:99240

InterPro

IPR006935 Helicase/UvrB domain
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF04851
PF00270

PRINTS

PIRSF

SMART

SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite