Version 5.4
Mus musculus Protein: Mdc1
Summary
InnateDB Protein IDBP-628304.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mdc1
Protein Name mediator of DNA damage checkpoint 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000133568
InnateDB Gene IDBG-179187 (Mdc1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 173 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 173 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0070975 FHA domain binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005925 focal adhesion
Protein Structure and Domains
PDB ID MGI:3525201
InterPro IPR000253 Forkhead-associated (FHA) domain
IPR008984 SMAD/FHA domain
PFAM PF00498
PRINTS
PIRSF
SMART SM00240
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3UX64
UniProt Splice Variant
Entrez Gene 240087
UniGene Mm.406559
RefSeq
MGI ID
MGI Symbol Mdc1
OMIM
CCDS
HPRD
IMGT
EMBL CR974451
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca