Version 5.4
Mus musculus Protein: Phox2b
Summary
InnateDB Protein IDBP-628305.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Phox2b
Protein Name paired-like homeobox 2b
Synonyms Dilp1; NBPhox; Pmx2b;
Species Mus musculus
Ensembl Protein ENSMUSP00000134216
InnateDB Gene IDBG-167759 (Phox2b)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001764 neuron migration
GO:0003357 noradrenergic neuron differentiation
GO:0006355 regulation of transcription, DNA-templated
GO:0008285 negative regulation of cell proliferation
GO:0010001 glial cell differentiation
GO:0021533 cell differentiation in hindbrain
GO:0021934 hindbrain tangential cell migration
GO:0030182 neuron differentiation
GO:0035914 skeletal muscle cell differentiation
GO:0045665 negative regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0048468 cell development
GO:0048839 inner ear development
GO:0048894 efferent axon development in a lateral line nerve
GO:0071773 cellular response to BMP stimulus
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1100882
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
PFAM PF00046
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8C741
UniProt Splice Variant
Entrez Gene 18935
UniGene Mm.62505
RefSeq
MGI ID
MGI Symbol Phox2b
OMIM
CCDS
HPRD
IMGT
EMBL AC119834 AK052579
GenPept BAC35048

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca