Version 5.4
Homo sapiens Protein: RSRC1
Summary
InnateDB Protein IDBP-63059.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RSRC1
Protein Name arginine/serine-rich coiled-coil 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000308671
InnateDB Gene IDBG-63055 (RSRC1)
Protein Structure
UniProt Annotation
Function Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing. {ECO:0000269PubMed:15798186}.
Subcellular Localization Nucleus {ECO:0000250}. Nucleus speckle {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Shuttles between the nucleus and cytoplasm. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006913 nucleocytoplasmic transport
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96IZ7
PhosphoSite PhosphoSite-Q96IZ7
TrEMBL
UniProt Splice Variant
Entrez Gene 51319
UniGene Hs.591283
RefSeq NP_001258763
HUGO HGNC:24152
OMIM 613352
CCDS CCDS63822
HPRD 18006
IMGT
EMBL AF208853 AK290334 BC006982 BC010357
GenPept AAF64267 AAH06982 AAH10357 BAF83023

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca