Version 5.4
Homo sapiens Protein: CAP2
Summary
InnateDB Protein IDBP-63273.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAP2
Protein Name CAP, adenylate cyclase-associated protein, 2 (yeast)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000229922
InnateDB Gene IDBG-63271 (CAP2)
Protein Structure
UniProt Annotation
Function May have a regulatory bifunctional role.
Subcellular Localization Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007163 establishment or maintenance of cell polarity
GO:0007165 signal transduction
GO:0007190 activation of adenylate cyclase activity
GO:0007411 axon guidance
Cellular Component
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR006599 CARP motif
IPR013912 Adenylate cyclase-associated CAP, C-terminal
IPR013992 Adenylate cyclase-associated CAP, N-terminal
PFAM PF08603
PF01213
PRINTS
PIRSF
SMART SM00673
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P40123
PhosphoSite PhosphoSite-P40123
TrEMBL
UniProt Splice Variant
Entrez Gene 10486
UniGene Hs.605285
RefSeq NP_006357
HUGO HGNC:20039
OMIM
CCDS CCDS4539
HPRD 10808
IMGT
EMBL AK312362 BC008481 CH471087 CR457022 U02390
GenPept AAA20587 AAH08481 BAG35280 CAG33303 EAW55380

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca