Version 5.4
Homo sapiens Protein: TXNDC9
Summary
InnateDB Protein IDBP-63333.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TXNDC9
Protein Name thioredoxin domain containing 9
Synonyms APACD; PHLP3;
Species Homo sapiens
Ensembl Protein ENSP00000264255
InnateDB Gene IDBG-63331 (TXNDC9)
Protein Structure
UniProt Annotation
Function Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin. {ECO:0000269PubMed:16415341}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0030496 midbody
Protein Structure and Domains
PDB ID
InterPro IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain
PFAM PF13098
PF13192
PF13462
PF13905
PF00085
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14530
PhosphoSite PhosphoSite-O14530
TrEMBL B8ZZX4
UniProt Splice Variant
Entrez Gene 10190
UniGene Hs.598321
RefSeq NP_005774
HUGO HGNC:24110
OMIM 612564
CCDS CCDS2044
HPRD 15592
IMGT
EMBL AB006679 AB451403 AC079447 AK222616 AK313777 BC005968 BC022864 BC070183 CH471127 CR456935
GenPept AAH05968 AAH22864 AAH70183 AAX93257 BAA21881 BAD96336 BAG36515 BAG70217 CAG33216 EAX01869 EAX01870

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca