Version 5.4
Homo sapiens Protein: CREG2
Summary
InnateDB Protein IDBP-63786.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CREG2
Protein Name cellular repressor of E1A-stimulated genes 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000315203
InnateDB Gene IDBG-63784 (CREG2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000269PubMed:12408961}.
Disease Associations
Tissue Specificity Brain specific mainly in the limbic system and faintly in the spinal cord but not in cerebellum. {ECO:0000269PubMed:12408961}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
Protein Structure and Domains
PDB ID
InterPro IPR012349 FMN-binding split barrel
IPR014631 Cellular repressor of E1A-stimulated genes (CREG)
PFAM
PRINTS
PIRSF PIRSF036911
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IUH2
PhosphoSite PhosphoSite-Q8IUH2
TrEMBL Q580X0
UniProt Splice Variant
Entrez Gene 200407
UniGene Hs.732289
RefSeq NP_722578
HUGO HGNC:14272
OMIM
CCDS CCDS2052
HPRD 16753
IMGT
EMBL AB046109 AC092570 AC099797 AK094970 BC032949 BC047514
GenPept AAH32949 AAH47514 AAX82005 AAX88886 BAC04464 BAC22189

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca