InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GH1

Summary

InnateDB Protein

IDBP-64282.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GH1

Protein Name

growth hormone 1

Synonyms

GH; GH-N; GHN; hGH-N; IGHD1B;

Species

Homo sapiens

Ensembl Protein

ENSP00000343791

InnateDB Gene

IDBG-543240 (GH1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005131	growth hormone receptor binding
GO:0005148	prolactin receptor binding
GO:0005179	hormone activity
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0046872	metal ion binding

Biological Process

GO:0007259	JAK-STAT cascade
GO:0010535	positive regulation of activation of JAK2 kinase activity
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015758	glucose transport
GO:0032355	response to estradiol
GO:0040018	positive regulation of multicellular organism growth
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0043406	positive regulation of MAP kinase activity
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
GO:0046427	positive regulation of JAK-STAT cascade
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0060396	growth hormone receptor signaling pathway
GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
GO:0070977	bone maturation