Version 5.4
Homo sapiens Protein: XRRA1
Summary
InnateDB Protein IDBP-64496.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XRRA1
Protein Name X-ray radiation resistance associated 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000339918
InnateDB Gene IDBG-64492 (XRRA1)
Protein Structure
UniProt Annotation
Function May be involved in the response of cells to X-ray radiation. {ECO:0000269PubMed:12908878}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:12908878}. Nucleus {ECO:0000269PubMed:12908878}.
Disease Associations
Tissue Specificity Expressed predominantly in testis followed by prostate and ovary. Low levels found in other tissues including peripheral blood leukocytes, spleen, thymus, small intestine and colon. Also expressed in neuroblastoma, glioma, breast, lung, leukemia, renal, ovarian, prostate and colorectal cancer cell lines. {ECO:0000269PubMed:12908878}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0010165 response to X-ray
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P2D8
PhosphoSite PhosphoSite-Q6P2D8
TrEMBL E9PJ58
UniProt Splice Variant
Entrez Gene 143570
UniGene Hs.739766
RefSeq NP_892014
HUGO HGNC:18868
OMIM 609788
CCDS CCDS44680
HPRD
IMGT
EMBL AF439934 AP000560 AP001992 AY163836 BC037294 BC064584 BK000541
GenPept AAH64584 AAO23657 AAP97315 DAA00367

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca