InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STX2

Summary

InnateDB Protein

IDBP-64740.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STX2

Protein Name

syntaxin 2

Synonyms

EPIM; EPM; STX2A; STX2B; STX2C;

Species

Homo sapiens

Ensembl Protein

ENSP00000261653

InnateDB Gene

IDBG-64736 (STX2)

Protein Structure

UniProt Annotation

Function

Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.

Subcellular Localization

Membrane; Single-pass type IV membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005484	SNAP receptor activity
GO:0005515	protein binding
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0006886	intracellular protein transport
GO:0007165	signal transduction
GO:0007340	acrosome reaction
GO:0007398	ectoderm development
GO:0009887	organ morphogenesis
GO:0010468	regulation of gene expression
GO:0016192	vesicle-mediated transport
GO:0030193	regulation of blood coagulation

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome