InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PLAGL2

Summary

InnateDB Protein

IDBP-64787.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLAGL2

Protein Name

pleiomorphic adenoma gene-like 2

Synonyms

ZNF900;

Species

Homo sapiens

Ensembl Protein

ENSP00000246229

InnateDB Gene

IDBG-64785 (PLAGL2)

Protein Structure

UniProt Annotation

Function

Shows weak transcriptional activatory activity.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	3 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006629	lipid metabolic process
GO:0009791	post-embryonic development
GO:0034378	chylomicron assembly
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway