Version 5.4
Homo sapiens Protein: SULT1C3
Summary
InnateDB Protein IDBP-64903.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SULT1C3
Protein Name sulfotransferase family, cytosolic, 1C, member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000333310
InnateDB Gene IDBG-64901 (SULT1C3)
Protein Structure
UniProt Annotation
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor and has low sulphotransferase activity towards various substrates with alcohol groups (in vitro). May catalyze the sulfate conjugation of xenobiotic compounds and endogenous substrates. {ECO:0000269PubMed:17425406, ECO:0000269PubMed:17936463}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Not detectable in any of the tissues tested. {ECO:0000269PubMed:14676822}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004027 alcohol sulfotransferase activity
GO:0004062 aryl sulfotransferase activity
GO:0008146 sulfotransferase activity
Biological Process
GO:0006790 sulfur compound metabolic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000863 Sulfotransferase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00685
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6IMI6
PhosphoSite PhosphoSite-Q6IMI6
TrEMBL
UniProt Splice Variant
Entrez Gene 442038
UniGene Hs.535156
RefSeq NP_001008743
HUGO HGNC:33543
OMIM
CCDS CCDS33267
HPRD 18131
IMGT
EMBL AC019100 BK001432
GenPept DAA01770 DAA01771

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca